Golden Helix

Actionable In-Silico Results.

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Overview

Golden Helix provides a suite of software products for genetic data analysis, primarily focused on the clinical and translational research markets. Their tools, including VarSeq, VS-CNV, and VS-Warehouse, enable users to process raw sequencing data, identify and annotate variants and copy number variations (CNVs), and create clinical-grade reports. The platform is designed to streamline the entire tertiary analysis workflow, from VCF file to final report.

✨ Key Features

  • Variant annotation and filtering (VarSeq)
  • Copy Number Variation (CNV) analysis (VS-CNV)
  • Clinical reporting and workflow automation
  • Centralized data warehousing (VS-Warehouse)
  • Support for germline and somatic analysis
  • Integration of public and proprietary annotations

🎯 Key Differentiators

  • Strong focus on integrated CNV analysis from NGS data
  • Highly flexible and customizable filtering and reporting workflows
  • Desktop-first approach provides speed and data security

Unique Value: Provides a powerful and efficient desktop-based solution for the entire clinical variant interpretation workflow, including robust CNV analysis, enabling labs to deliver high-quality clinical reports.

🎯 Use Cases (4)

Clinical genetic testing for rare diseases Cancer genomics and tumor profiling Pharmacogenomics Translational research

✅ Best For

  • Implementing ACMG/AMP guidelines for variant classification
  • Detecting and interpreting CNVs from NGS data
  • Creating customized clinical reports for diagnostic labs

💡 Check With Vendor

Verify these considerations match your specific requirements:

  • Primary and secondary NGS data analysis (e.g., alignment, base calling)
  • Basic molecular biology research (e.g., cloning)

🏆 Alternatives

Fabric Genomics Genoox QIAGEN Ingenuity Variant Analysis

Offers one of the most advanced and integrated solutions for CNV analysis from NGS data, a feature that is often less developed in other clinical interpretation platforms. Its desktop nature also appeals to labs with concerns about cloud security.

💻 Platforms

Desktop (Windows, macOS, Linux)

✅ Offline Mode Available

🔌 Integrations

Public annotation sources (ClinVar, gnomAD, etc.) LIMS systems Custom databases

🛟 Support Options

  • ✓ Email Support
  • ✓ Phone Support
  • ✓ Dedicated Support (All tier)

🔒 Compliance & Security

✓ HIPAA ✓ BAA Available ✓ GDPR ✓ HIPAA ✓ GDPR

💰 Pricing

Contact for pricing

✓ 14-day free trial

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