OpenClinica

The eClinical platform for patient-centric research.

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Overview

OpenClinica is a leading open source electronic data capture (EDC) platform for clinical research. While its primary function is data collection and management for clinical trials, it includes features for data extraction and integration with statistical software for analysis. It helps make clinical trial data more organized, secure, and ready for biostatistical review.

✨ Key Features

  • 21 CFR Part 11 compliant electronic data capture (EDC)
  • Electronic patient-reported outcomes (ePRO)
  • Randomization and trial supply management (RTSM)
  • Data extraction in multiple formats (SPSS, SAS, CDISC)
  • Real-time data validation and query management

🎯 Key Differentiators

  • Open source foundation provides flexibility
  • Strong focus on patient-centric features like ePRO
  • Compliance with key clinical trial regulations (21 CFR Part 11)

Unique Value: Provides a compliant and feature-rich platform for capturing clinical trial data, ensuring data quality and integrity from the start, which is the foundation of any valid biostatistical analysis.

🎯 Use Cases (4)

Academic clinical trials Medical device studies Biotech and pharmaceutical trials Public health research

✅ Best For

  • Capturing and managing patient data for a multi-site oncology trial.
  • Deploying ePRO forms for patients to complete at home.

💡 Check With Vendor

Verify these considerations match your specific requirements:

  • Users who need to perform the statistical analysis itself within the tool
  • Basic laboratory research not involving clinical trials

🏆 Alternatives

REDCap Medidata Rave Veeva Vault EDC

While not a statistical analysis tool itself, OpenClinica is a critical upstream component. Compared to REDCap, it offers a commercially supported, validated SaaS option with a stronger focus on regulatory compliance for industry trials.

💻 Platforms

Web API

🔌 Integrations

SAS SPSS Medidata Rave API

🛟 Support Options

  • ✓ Email Support
  • ✓ Live Chat
  • ✓ Phone Support
  • ✓ Dedicated Support (Enterprise tier)

🔒 Compliance & Security

✓ SOC 2 ✓ HIPAA ✓ BAA Available ✓ GDPR ✓ ISO 27001 ✓ SSO ✓ 21 CFR Part 11 ✓ HIPAA ✓ GDPR ✓ ISO 27001

💰 Pricing

Contact for pricing
Free Tier Available

✓ 14-day free trial

Free tier: Open source community edition is available for self-hosting.

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